Azvudine - Wikipedia
Azvudine is an antiviral drug which acts as a reverse transcriptase inhibitor. [3] It was discovered for the treatment of hepatitis C [4] and has since been investigated for use against other viral diseases such as AIDS and COVID-19, [2] [5] for which it was granted conditional approval in China. [6] [7] Azvudine was first discovered in 2007. [8]
Oral Azvudine for hospitalised patients with COVID-19 and pre …
A randomized, open-label, controlled clinical trial of Azvudine tablets in the treatment of mild and common COVID-19, a pilot study
阿兹夫定 - 百度百科
阿兹夫定（Azvudine），又称阿滋福啶，由常俊标教授发明，河南真实生物科技有限公司、郑州大学、河南师范大学、河南省科学院高新技术研究中心共同研发。
Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in …
2021年12月6日 · Azvudine (FNC) is a nucleoside analog that inhibits HIV-1 RNA-dependent RNA polymerase (RdRp). Recently, we discovered FNC an agent against SARS-CoV-2, and have taken it into Phase III trial for...
Azvudine (FNC): a promising clinical candidate for COVID-19
2020年10月10日 · To evaluate the efficacy and safety of FNC in patients with mild and common COVID-19, we recently conducted a randomized, open-label, controlled clinical trial of FNC tablets in China...
阿兹夫定 - 维基百科，自由的百科全书
阿兹夫定 （简称 FNC）是 中国大陆 河南真实生物科技有限公司 研发的 抗病毒药物，用于治疗 艾滋病 [3] 和 2019冠状病毒病 [4]。 此物属 核苷类 小分子药物，有 逆转录酶抑制剂 、 vif 抑制剂、RNA病毒聚合酶抑制剂三种活性 [5]。 阿兹夫定在2022年7月作为艾滋病药物售价是25.86元人民币/mg（片），每日推荐剂量3 mg。 [6] 2022年11月，作为2019冠状病毒病药物的价格为每周350元（一瓶35片×1 mg/片）。 [7] 阿兹夫定在中国受条件批准用于“与核苷逆转录酶抑制剂及非核 …
使用国产新冠口服药「阿兹夫定」，这些要点需要了解！ - 丁香园
2023年1月4日 · 阿兹夫定（Azvudine） 是新型核苷类逆转录酶和辅助蛋白 Vif（Viral infectivity factor）双靶点抑制剂，是我国拥有完全自主知识产权并拥有全球专利的抗病毒 1.1 类创新药物 [1-5] 。
A Randomized, Open-Label, Controlled Clinical Trial of Azvudine Tablets ...
Thus, this randomized, open-label, controlled clinical trial (ChiCTR2000029853) was performed in China. A total of 20 mild and common COVID-19 patients were enrolled and randomly assigned to receive azvudine and symptomatic treatment (FNC group), or standard antiviral and symptomatic treatment (control group).
A very recent work published in Advanced Science by our group reveals that 2′-deoxy-2′-β-fluoro-4′-azidocytidine (Azvudine, FNC), a clinical candidate originally developed for HIV treatment, has...
A Randomized, Open‐Label, Controlled Clinical Trial of Azvudine Tablets ...
2020年7月14日 · This pilot study is a randomized, open, controlled clinical trial to evaluate the efficacy and safety of azvudine tablets in the treatment of COVID-19. Our trial found that azvudine may shorten the time of nucleic acid negativity conversion of persistent mild and common COVID-19 patient versus standard antiviral therapy.
- 某些结果已被删除